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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR4A1 All Species: 15.45
Human Site: S225 Identified Species: 30.91
UniProt: P22736 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22736 NP_002126.2 598 64463 S225 L G E G E S Y S M P T A F P G
Chimpanzee Pan troglodytes XP_509073 802 86293 S429 L G E G E S Y S M P T A F P G
Rhesus Macaque Macaca mulatta XP_001085399 734 78645 S361 L G E G E S Y S M P T A F P G
Dog Lupus familis XP_535920 598 66603 S229 N P I R K P A S M G F P G L Q
Cat Felis silvestris
Mouse Mus musculus P12813 601 64720 S228 L G E G E S Y S M P A A F P G
Rat Rattus norvegicus P22829 597 64263 V225 G E G E S Y S V P A A F P G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508960 521 58059 Y198 D N A A C Q H Y G V R T C E G
Chicken Gallus gallus XP_422166 598 66280 R225 F A V P S P I R K Q P A M A F
Frog Xenopus laevis Q04913 577 64365 V225 P G V L D S S V L L D S P L S
Zebra Danio Brachydanio rerio NP_001002173 574 63026 L225 S G L M D G H L S P K V R S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49869 1073 116973 N702 K L A K I T L N Q R H S H A H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41829 619 68604 S226 G T P S P H S S S L P T S P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.9 80.7 56.6 N.A. 91.3 91.4 N.A. 49.6 57 65.8 58.7 N.A. 31.2 N.A. 28.4 N.A.
Protein Similarity: 100 73.9 81 70.4 N.A. 93.8 94.1 N.A. 61.8 70.4 77.4 70.4 N.A. 40.5 N.A. 41.5 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 93.3 0 N.A. 6.6 6.6 13.3 13.3 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 20 N.A. 93.3 0 N.A. 13.3 6.6 33.3 26.6 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 9 0 0 9 0 0 9 17 42 0 17 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 17 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 9 34 9 34 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 9 9 34 0 9 % F
% Gly: 17 50 9 34 0 9 0 0 9 9 0 0 9 9 42 % G
% His: 0 0 0 0 0 9 17 0 0 0 9 0 9 0 9 % H
% Ile: 0 0 9 0 9 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 9 9 0 0 0 9 0 9 0 0 0 0 % K
% Leu: 34 9 9 9 0 0 9 9 9 17 0 0 0 17 9 % L
% Met: 0 0 0 9 0 0 0 0 42 0 0 0 9 0 0 % M
% Asn: 9 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 9 9 9 9 9 17 0 0 9 42 17 9 17 42 17 % P
% Gln: 0 0 0 0 0 9 0 0 9 9 0 0 0 0 9 % Q
% Arg: 0 0 0 9 0 0 0 9 0 9 9 0 9 0 0 % R
% Ser: 9 0 0 9 17 42 25 50 17 0 0 17 9 9 9 % S
% Thr: 0 9 0 0 0 9 0 0 0 0 25 17 0 0 0 % T
% Val: 0 0 17 0 0 0 0 17 0 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 34 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _